What are the opening hours?

Monday 8am - 8pm Tuesday 8am - 8pm Wednesday 8am - 8pm Thursday 8am - 8pm Friday 8am - 8pm Saturday 9am - 6pm

Lewis Drug

Stop in to your downtown Sioux Falls Lewis at 10th Street & Phillips Avenue to pick up everything you need at home or at the office!

We offer a wide selection of name brands and specialty items, always at affordable prices. Our conveniently located store offers all of your everyday essentials including home & beauty supplies, grab-and-go meals, groceries, and more!

11/02/2026

Lewis' annual Ladies Event is only 2 days away! Enjoy 20% off everything in-store* November 4–5. Plus, register on the Lewis App for a chance to win bonus app rewards

*Some exclusions apply.

11/01/2026

Lewis' annual Ladies Event is only 3 days away! Enjoy 20% off everything in-store* November 4–5. Plus, register on the Lewis App for a chance to win bonus app rewards

*Some exclusions apply.

10/31/2026

Lewis' annual Ladies Event is only 4 days away! Enjoy 20% off everything in-store* November 4–5. Plus, register on the Lewis App for a chance to win bonus app rewards

*Some exclusions apply.

10/30/2026

Lewis Pharmacy is now accepting Wellcare in 2027!

10/30/2026

Lewis' annual Ladies Event is only 5 days away! Enjoy 20% off everything in-store* November 4–5. Plus, register on the Lewis App for a chance to win bonus app rewards

*Some exclusions apply.

10/30/2026

Ladies Event is coming up quickly 💃 And we want to show you more of what will be there. You may already know you can get 20% off EVERYTHING*, but see more of what's in store during our annual Ladies Event on November 4 & 5.

*Some exclusions apply.

10/28/2026

The holiday kickoff is nearly here! 🤩🛒 November 4th & 5th will be here sooner than you think. Plan your shopping trip today, where you can save 20% off EVERYTHING*! Tell us what you're most excited to find during this year's Ladies Event.

*Exclusions apply.

Find the store nearest you so you can keep on saving.

10/28/2026

🎄 $100 LEWIS APP REWARD UP FOR GRABS! Show us your favorite outdoor Christmas displays for a chance to win a $100 Lewis App reward!

Snap a photo of your favorite outdoor Christmas display you've seen this year for a chance to win! We’ll randomly select one winner from all eligible entries across Facebook and Instagram. Giveaway ends November 3, and the winner will be contacted by direct message shortly after. No purchase necessary. This giveaway is not sponsored, endorsed, or administered by Meta.

And we wanted to lighten and up even more! Spend $100 or more on qualifying outdoor décor and get $15 off instantly with the Lewis App from October 28 through November 3.

10/28/2026

This Week’s Ad is Here
Find deals at Lewis from October 28th - November 3rd. View the full ad on our website or in the Lewis app.

Address

136 South Phillips Avenue
Sioux Falls, SD
57104

Opening Hours

Monday	8am - 8pm
Tuesday	8am - 8pm
Wednesday	8am - 8pm
Thursday	8am - 8pm
Friday	8am - 8pm
Saturday	9am - 6pm

Website

https://www.lewisdrug.com/stores/lewis-10th-phillips-sioux-falls

Alerts

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